Whartons Jelly and Amniotic Fluid

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Whartons Jelly and Amniotic Fluid

Wharton's Jelly And Mesenchymal Stem Cells

Mesenchymal stem cells (MSCs) are natural cells produced by our bodies that offer regenerative potential, slowing or halting chronic disease as well as improving function and pain in joints, ligaments, and muscles. MSCs can be harvested from a patient’s own bone marrow, adipose tissue, or from healthy donated allogeneic homologous umbilical cord (UC)-derived tissue rich in Wharton’s Jelly.

Wharton’s Jelly

A recent 2020 randomized study analyzed the number of growth factors, cytokines, hyaluronic acid, and extracellular vesicles in donor-selected umbilical cord tissue-derived Wharton’s Jelly.

The results indicate a higher number of numerous growth factors present in Wharton’s Jelly UC-derived allogenic tissue, compared to bone-marrow aspirate or adipose tissue MSCs, which is why here at All Star Health we are treating our patients with UC-derived Wharton’s Jelly tissue for regenerative therapy.

What is amniotic fluid therapy?

Amniotic tissue contains hyaluronic acid (HA); HA is a natural component of normal knee fluid. Hyaluronic acid has natural lubricating and anti-inflammatory properties. This fluid is also known to be rich in beneficial growth factors that can be helpful in joints affected by arthritis and inflammation. Amniotic fluid is typically harvested from healthy donors by a third party. After harvest, the fluid is carefully screened for sterility before being made available for clinical use. This tissue may be used as a solo injection or in combination with certain surgical procedures.

Who would benefit from Amniotic Fluid Therapy?

The best candidates for amniotic fluid therapy are patients with joint pain associated with mild to moderate joint arthritis. The ideal patient has joint pain but is not quite ready for a surgical procedure. Patients who have failed treatment with other knee injections (cortisone, gel shots) may find this particular therapy most useful. Patients being treated for the management of chronic OA may also benefit from amniotic fluid as a maintenance therapy.

Does obtaining amniotic fluid for use in orthopedic medicine harm the baby or mother?

The manner in which amniotic fluid is collected for use in orthopedic medicine does not harm the baby or the mother. Therapeutic amniotic fluid used is obtained after a healthy baby is born or after a full-term caesarean section. This fluid used to be considered medical waste; in many cases this fluid can be utilized in orthopedic medicine. Amniotic fluid is only collected after the birth mother has given consent. The fluid is then processed, screened, sterilized, and finally frozen for future use.